Maternal Cardiovascular Function in Normal Pregnancy

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Maternal Cardiovascular Function in Normal Pregnancy

Understanding cardiovascular physiological adaptation to pregnancy is particularly important in elucidating the pathophysiology and management of hypertensive disorders of pregnancy—still one of the most common causes of maternal morbidity and mortality worldwide. Functional changes of the heart in pregnancy have been widely investigated during the last few decades with relatively inconsistent ...

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Maternal Cardiovascular Function in Normal Pregnancy

Understanding cardiovascular physiological adaptation to pregnancy is particularly important in elucidating the pathophysiology and management of hypertensive disorders of pregnancy—still one of the most common causes of maternal morbidity and mortality worldwide. Functional changes of the heart in pregnancy have been widely investigated during the last few decades with relatively inconsistent ...

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Maternal visfatin concentration in normal pregnancy.

OBJECTIVE Adipose tissue has now emerged as a powerful endocrine organ via the production of adipokines. Visfatin, a novel adipokine with diabetogenic and immuno-modulatory properties has been implicated in the pathophysiology of insulin resistance in patients with obesity and Type-2 diabetes mellitus. The aim of this study was to determine whether there are changes in the maternal plasma conce...

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Cardiovascular function in mice during normal pregnancy and in the absence of endothelial NO synthase.

In humans, the increased cardiovascular demands of pregnancy are met by increases in cardiac output (CO), stroke volume (SV), plasma volume (PV), and cardiac and aortic inner dimensions and a concurrent decrease in arterial pressure that indicates a fall in total peripheral vascular resistance. The mechanisms responsible for these changes are incompletely understood, but NO synthase (NOS) is be...

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Thyroid function in pregnancy: what is normal?

BACKGROUND Gestational thyroid dysfunction is common and associated with maternal and child morbidity and mortality. During pregnancy, profound changes in thyroid physiology occur, resulting in different thyroid-stimulating hormone (TSH) and free thyroxine (FT4) reference intervals compared to the nonpregnant state. Therefore, international guidelines recommend calculating trimester- and assay-...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2016

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.115.06667